Journal Article

Gouania willdenowi is a teleost fish without immunoglobulin genes

Mirete-Bachiller, S., Olivieri, D.N., Gambón-Deza, F.

Record Number:
4896
Year:
2019
Journal:
bioRxiv Preprint
PMCID:
https://doi.org/10.1101/793695
Abstract:
In the study of immunoglobulin V genes in fish genomes, we found that the species Gouania willdenowi does not possess any such regions, neither for the heavy chain nor for the light chains. Also, genes that code for the immunoglobulin constant regions were also not found. A detailed analysis of the chromosomal region of these genes revealed a deletion in the entire locus for regions of the heavy and light chains. These studies provide evidence that this species does not possess genes coding for immunoglobulins. Additionally, we found the genes that code for CD79a and CD79b protein molecules have also been deleted. Regions for the T = lymphocyte receptors are present but the T receptors were not found. In transcripts of two other Gobiesocidae species, Acystus sp. and Tomicodon sp., no antibody sequences could be detected, possibly indicating the absence of immunoglobulins in all species of this family. Keywords: Gobiesocidae, Immunoglobulins, B cell receptor
Times Cited:
5
Relevent Species:
Gouania adriatica Wagner, Kovačić and Koblmüller 2020Gouania orientalis Wagner, Kovačić and Koblmüller 2020Gouania hofrichteri Wagner, Kovačić and Koblmüller 2020Gouania pigra (Nardo 1827)Gouania willdenowi (Risso 1810)