Conference Paper

Morphological variations in eye size: does rx3 play a role?

Sifuentes-Romero I. and Kowalko, J.E.

Record Number:
4295
Year:
2019
Abstract:
In vertebrates, eyes form from a single eye field, specified from the neural epithelium during gastrulation. Under the influence of multiple signaling factors, this field splits into two bilateral regions each containing the primordium of both retina and lens. During neurulation, the retina primordium evaginates laterally from the forebrain, giving rise to the optic vesicles, the first morphological eye features that form. Several transcription factors required for optic vesicle development have been identified; among them, the retinal homeobox transcription factor, RX (also known as retina and anterior neural fold homeobox, RAX) has an evolutionarily conserved role during early vertebrate eye development. Loss of function mutations in Rx/Rax in mammals or rx3 in fish, result in loss of optic vesicle evagination and a complete lack of eyes. Additionally, in humans RAX has been associated with structural eye defects such as anophthalmia (absence of eyes) or microphthalmia (small eyes), but the actual role that RAX plays in these morphological variations in eye size is still unknown. Astyanax mexicanus is a single species consisting of eyed surface-dwelling (surface fish) and blind cave-dwelling (cavefish) morphs. Surface fish develop large eyes while cavefish initiate eye development. However, developmental alterations in cavefish lead to differences in eye size and morphogenesis, and ultimately result in the degeneration of the eye. These distinct morphological differences that arise during development make Astyanax a powerful system for studying the genetic regulation of eye size. Furthermore, previous studies demonstrated that rx3 is located under a QTL for eye size in the Astyanax mexicanus cavefish, suggesting that this gene may play a role in the evolution of eye size reduction in cavefish. We conducted gene expression analyses to quantify levels of expression and determine the rx3 expression domain in embryos of surface fish and two independentlyevolved cavefish populations. Our data suggest that the rx3 expression domain is reduced in size early in Pachon cavefish development. Interestingly, this reduction in rx3 expression domain size was not as pronounced in Molino cavefish, suggesting that different molecular and developmental mechanisms underlie reduced eye size in these two cave populations. Further, we have recently used CRISPR/Cas9 gene-editing to generate surface fish with mutations in rx3. Injected surface fish have eyes that are greatly reduced in size or entirely absent compared to uninjected siblings, suggesting a conserved role for this gene in early eye development in Astyanax mexicanus. We are currently isolating rx3 mutant lines of fish to examine the role of regulation of expression of this gene in eye size. Together, these results will allow us to unravel the role that rx3 is playing during eye development and how differences in rx3 expression regulate differences in eye morphogenesis, critical to understanding the mechanisms that lead to different congenital eye disorders.
Times Cited:
1
Conference Name:
Astyanax Interrnational Meeting
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(1964)Thines, G., Wolff-Van Ermengem, F., Boucquey, C. and Soffie, M. (1965)Boucquey, C., Thines, G. and Van Der Borght, C. (1965)Carmignani, M. P. A. (1966)Cavicchioli, G. and Guarnieri, P. (1966)Peters, N. and Peters, G. (1966)Thines, G., Soffie, M. and Vandenbussche, E. (1966)Reed, M. (1966)Sadoglu, P. (1967)Schemmel, C. (1967)Pfeiffer, W. (1967)Pfeiffer, W. (1967)Popper, A. N. and Tavolga, W. N. (1967)Walters, V. and Liu, R. K. (1967)Mattheij, J. A. (1968)Mattheij, J. A. (1968)Wilkens, H. (1968)Carmignani, M. P. A. (1968)Weiss, B. A. (1969)Mattheij, J. A. (1969)Mattheij, J. A. and Sprangers, J. A. P. (1969)Sadoglu, P. and McKee, A. (1969)Weiss, B. and Martini, J. (1970)Whitt, G. S. and Maeda, F. S. (1970)Mattheij, J. A. (1970)Mattheij, J. A. (1970)Wilkens, H. (1970)Wilkens, H. (1970)Wilkens, H. (1970)Gertychowa, R. (1970)Gertychowa, R. (1970)Popper, A. N. (1970)Wiley, S. and Mitchell, R. W. (1971)Wiley, S. and Mitchell, R. W. (1971)Zaccone, G. (1971)Wilkens, H. (1971)Gertychowa, R. (1971)Popper, A. N. (1971)Zaccone, G. (1972)Wilkens, H. (1972)Wilkens, H. (1972)Wilkens, H. (1972)Avise, J. C. and Selander, R. K. (1972)Thines, G. and Wissocq, N. (1972)Wilkens, H. and Burns, R. J. (1972)Mitchell, R. W. (1973)Yasuda, K. (1973)Zeitlin, S. M. (1973)Zeitlin, S. M. and McDevitt, D. S. (1973)Schemmel, C. (1973)Thines, G. and LeGrain, J. M. (1973)Durand, J. P. (1973)Voneida, T. J. (1973)Chakraborty, R. and Nei, M. (1974)Schemmel, C. (1974)Schemmel, C. (1974)Sligar, C. (1974)Omura, Y. (1975)Sadoglu, P. (1975)Peters, N., Scholl, A. and Wilkens, H. (1975)Wilkens, H. (1976)Sligar, C. and Voneida, T. J. (1976)Herwig, H. J. (1976)Durand, J. P. (1976)Herwig, H. J. (1976)Voneida, T. J. and Sligar, C. (1976)Erckens, W. and Weber, F. (1976)Mitchell, R. W., Russell, W. H. and Elliott, W. R. (1977)Yew, D. T. and Yoshihara, H. M. (1977)Kirby, R. F., Thompson, K. W. and Hubbs, C. (1977)Zaccone, G. (1977)Wilkens, H. (1977)Thines, G. and Weyers, M. (1978)Durand, J. P. (1978)Sadoglu, P. (1979)Durand, J. P. (1979)Wilkens, H., Peters, H. and Schemmel, C. (1979)Woodhead, A. D. and Achey, P. M. (1979)Weissert, R. (1980)Schemmel, C. (1980)Wilkens, H. (1980)Wilkens, H. (1980)Quinn, T. P. (1980)Weissert, R. and Campenhausen, C. (1981)Campenhausen, C., Riess, I. and Weissert, R. (1981)Reddell, J. R. (1981)Herwig, H. J. (1981)Rose, F. L. and Mitchell, R. W. (1982)Jankowska, M. and Thines, G. (1982)Lamprecht, G. and Weber, F. (1982)Tabata, M. (1982)Erckens, W. and Martin, W. (1982)Erckens, W. and Martin, W. (1982)Parzefall, J. (1983)Zilles, K., Tillmann, B. and Bennemann, R. (1983)Romero, A. (1983)Romero, A. (1984)Schuppa, M. (1984)Wilkens, H. (1984)Voneida, T. J. and Fish, S. E. (1984)Romero, A. (1984)Romero, A. (1985)Burchards, H., Dolle, A. and Parzefall, J. (1985)Lamprecht, G. and Weber, F. (1985)Teyke, T. (1985)Wilkens, H. (1985)Romero, A. (1986)Parzefall, J. (1986)De Fraipont, M. (1986)Fraipont, M. (1986)Wilkens, H. (1986)De Fraipont, M. and Thines, G. (1986)Hassan, E. S. (1986)De Fraipont, M. and Thines, G. (1986)Wilkens, H. and Huppop, K. (1986)Huppop, K. (1986)Huppop, K. (1987)De Fraipont, M. (1987)De Fraipont, M. (1987)Wilkens, H. (1987)Huppop, K. (1988)Coombs, S., Janssen, J. and Webb, J. (1988)Fricke, D. (1988)Teyke, T. (1988)De Fraipont, M. (1988)Wilkens, H. (1988)Huppop, K. (1989)Fack, H. and Wilkens, H. (1989)Langecker, T. G. (1989)Fricke, D. and Parzefall, J. (1989)Teyke, T. (1989)Hassan, E. S. (1989)Yokoyama, R. and Yokoyama, S. (1990)Yokoyama, R and Yokoyama, S (1990)Klimpel, B. and Parzefall, J. (1990)Parzefall, J. and Fricke, D. (1990)Abdel-Latif, H., Hassan, E. S. and von Campenhausen, C. (1990)Peters, N., Schmidt, W. and Fricke, D. (1990)Langecker, T. G. (1990)Teyke, T. (1990)Huppop, K. and Wilkens, H. (1991)Huppop, K. (1991)Campenhausen, C. (1991)Parzefall, J. and Fricke, D. (1991)Langecker, T. G., Wilkens, H. and Junge, P. (1991)Bensouilah, M. and Denizot, J.P. (1991)Riedel, G. and Krug, L. (1991)Parzefall, J. (1992)Parzefall, J. (1992)Coombs S., Janssen J. and Montgomery J. (1992)Lamprecht, G. and Weber, F. (1992)Langecker, T. G. and Longley, G. (1992)De Fraipont, M. (1992)Wilkens, H. (1992)Hassan, E. S., Abdel-Latif, H. and Biebricher, R. (1992)Wilkens, H. and Meyer, M. (1992)Parzefall, J. (1993)Peters, N., Schacht, V., Schmidt, W. and Wilkens, H. (1993)Langecker, T. G. (1993)Langecker, T. G., Schmale, H. and Wilkens, H. (1993)Langecker, T. G., Schmale, H. and Wilkens, H. (1993)Hoffman, S. and Hausberg, C. (1993)Teyke, T. and Schaerer, S. (1994)Borowsky, R. (1994)Yokoyama, S., Meany, A., Wilkens, H. and Yokoyama, R. (1995)Langecker, T. G., Neumann, B., Hausberg, C. and Parzefall, J. (1995)Langecker, T. G., Wilkens, H. and Schmale, H. (1995)Borowsky, R. (1996)Behrens, M., Langecker, T.G., Wilkens, H. and Schmale, H. (1997)Riedel, G. (1997)Borowsky, R. and Espinasa, L. (1997)Riedel, G. and Krug, L. (1997)Jeffery, WR and Martasian, DP (1998)Behrens, M, Wilkens, H and Schmale, H (1998)Contreras-Balderas, S. and Lozano-Vilano, M.D.L. (1998)Wilkens, H. (1998)Kullander, S. O. (1999)Baker, CF and Montgomery, J (1999)Yamamoto, Y. and Jeffery, W. R. (2000)Espinasa, L. and Borowsky, R. (2000)Jeffery, W. R., Strickler, A.G., Guiney, S., Heyser, D.G. and Tomarev, S.I. (2000)Ford, D.C. (2000)Espinasa, L. and Borowsky, R. (2001)Montgomery, J.C., Coombs, S. and Baker, C.F. (2001)Jeffery, W. R. (2001)Strickler, A.G., Yamamoto, Y. and Jeffery, W. R. (2001)Boudriot, F and Reutter, K (2001)Romero, A., Jeffery, W.R. and Yamamoto, Y. (2002)Coombs, S, New, JG and Nelson, M (2002)Strickler, AG, Famuditimi, K and Jeffery, WR (2002)Berg, A. and Watson, G.M. (2002)Krejca, J. (2002)Dowling, TE, Martasian, DP and Jeffery, WR (2002)Borowsky, RL and Wilkens, H (2002)Strecker, U. (2003)Sarma, SSS, Lopez-Romulo, A and Nandini, S (2003)Strecker, U., Bernatchez, L. and Wilkens, H. (2003)Valdez-Moreno, M. and Contreras-Balderas, S. (2003)Contreras-Balderas, S, Almada-Villela, P, Lozano-Vilano, M de L and Garcia-Ramirez, ME (2003)Porter, M.L. and Crandall, K.A. (2003)Wilkens, H. and Strecker, U. (2003)McCauley, DW, Hixon, E and Jeffery, WR (2004)Jeffery, WR (2005)Jeffery, WR (2005)Espinasa, L., Yamamoto, Y. and Jeffery, W.R. (2005)Protas ME, Hersey C, Kochanek D, Zhou Y, Wilkens H, Jeffery WR, Zon LI, Borowsky R, Tabin CJ. (2006)Peleshanko, S, Julian, MD, Ornatska, M, McConney, ME, LeMieux, MC, Chen, NN, Tucker, C, Yang, YC, Liu, C, Humphrey, JAC and Tsukruk, VV (2007)Protas, M., Conrad, M., Gross, J.B., Tabin, C. and Borowsky, R.L. (2007)Windsor, S, Mallinson, G and Montgomery, J (2008)Windsor, S, Tan, D and Montgomery, J (2008)Windsor, S.P. (2008)Protas, M, Tabansky, I, Conrad, M, Gross, JB, Vidal, O, Tabin, C and Borowsky, RL (2008)Gross, J.B., Protas, M., Conrad, M., Scheid, P.E., Vidal, O., Jeffery, W.R., Tabin, C. and others (2008)Salin, K, Voituron, Y, Colson, C and Hervant, F (2008)Windsor, S (2009)Patton, P, Coombs, S and Windsor, S (2009)Jeffery, WR (2009)Sharma, S, Coombs, S, Patton, P and Burt de Perera, T (2009)McConney, ME, Chen, NN, Lu, D, Hu, H, Coombs, S, Liu, C and Tsukruk, VV (2009)Coombs, S and Patton, P (2009)Kowalko, J, Gross, JB, Protas, M, Borowsky, RL and Tabin, C (2009)Yamamoto, Y, Byerly, MS, Jackman, WR and Jeffery, WR (2009)Varatharasan, N., Croll, R. and Franz-Odendaal, T. (2009)Patton, P, Windsor, S and Coombs, S (2010)Windsor, S.P., Norris, S.E., Cameron, S.M., Mallinson, G.D. and Montgomery, J.C. (2010)Windsor, S.P., Norris, S.E., Cameron, S.M., Mallinson, G.D. and Montgomery, J.C. (2010)Van Trump, W.J., Coombs, S., Duncan, K. et al. (2010)Salin, K., Voituron, Y., Mourin, J. and Hervant, F. (2010)Salin, K, Voituron, Y, Mourin, J and Hervant, F (2011)Bradic, M, Beerli, P and Borowsky, RL (2011)Esquivel-Bobadilla, S (2011)Windsor, S, Paris, J and Burt de Perera, T (2011)Yamamoto, Y. and Jeffery, W.R. (2011)Tan, D, Patton, P and Coombs, S (2011)Kowalko, J, Rohner, N, Borowsky, RL and Tabin, C (2011)Kish, P.E., Bohnsack, B.L., Gallina, D., Kasprick, D.S. and Kahana, A. (2011)Gross, J.B. (2012)Hervant, F. (2012)Bradic, M., Beerli, P., Garcia-de Leon, F. J., Esquivel-Bobadilla, S. and Borowsky, R. L. (2012)Idda, M.L., Bertolucci, C., Vallone, D., Gothilf, Y., Sánchez-Vázquez, F.J. and Foulkes N.S. (2012)Jeffery, W.R. (2012)Wilkens, H. (2012)Trontelj, P. (2012)Dufton, M, Hall, BK and Franz-Odendaal, T. (2012)Protas, M. and Jeffery, W. R. (2012)Mogdans, J. and Bleckmann, H. (2012)Bradic, M., Teotonio, H. and Borowsky, R. L. (2013)Bibliowicz, J., Alie, A., Espinasa, L., Yoshizawa, M., Blin, M., Hinaux, H., Legendre, L., Pere, S. and Retaux, S. (2013)Pennisi, E. (2013)Pazza, R (2013)Kowalko, J.E., Rohner, N., Rompani, S.B., Peterson, B.K., Linden, T.A., Yoshizawa, M., Kay, E.H., Weber, J., Hoekstra, H.E., Jeffery, W.R., Borowsky, R. and Tabin, C.J. (2013)Rohner, N., Jarosz, D.F., Kowalko, J.E., Yoshizawa, M., Jeffery, W.R., Borowsky, R.L., Lindquist, S. and Tabin, C.J. (2013)Rohner, N (2013)Kowalko, J., Rohner, N., Linden, T.A., Rompani S.B., Warren, W.C., Borowsky, R., Tabin, C.J., Jeffery, W.R. and Yoshizawa M. (2013)Atukorala, A. D. S., Hammer, C., Dufton, M. and Franz-Odendaal, T. A. (2013)Gross, J.B., Furterer, A., Carlson, B.M. and Stahl, B.A. (2013)Stahl, B. A. and Gross, J. B. (2013)Beale, A., Guibal, C., Tamai, T. K., Klotz, L., Cowen, S., Peyric, E., Reynoso, V. H., Yamamoto, Y. and Whitmore, D. (2013)Stahl, AL (2013)Beale, A. (2013)Elliott, William R. (2013)Windsor, S.P. (2014)Moran, D., Softley, R. and Warrant, E.J. (2014)Montgomery, J., Bleckmann, H. and Coombs, S. (2014)Coombs, S., Bleckmann, H., Fay, R.R. and Popper, A.N. 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J. (2015)Aspiras, A.C., Rohner, N., Martineau, B., Borowsky, R.L. and Tabin, C.J. (2015)Devos, Lucie, Alie, A. and Retaux, S (2015)Bradic, M, Rohner, N, Tabin, C and Borowsky, R. (2015)Rohner, N (2015)Hernandez, D (2015)Stemmer, M., Schuhmacher, L.-N., Foulkes, N.S., Bertolucci, C. and Wittbrodt, J. (2015)O'Quin, Kelly E., Doshi, Pooja, Lyon, Anastasia, Hoenemeyer, Emma, Yoshizawa, Masato and Jeffery, William R. (2015)Silva, D. M. Z. A., Utsunomia, R., Pansonato-Alves, J.C., Oliveira, C. and Foresti, F. (2015)Moran, D., Softley, R. and Warrant, E.J. (2015)Hinaux, H., Blin, M., Fumey, J., Legendre, L., Heuze, A., Casane, D. and Retaux, S. (2015)Fumey, J. (2015)Carlson, B.M., Onusko, S.W. and Gross, J.B. (2015)Kulpa, Matthew, Bak-Coleman, Joseph and Coombs, Sheryl (2015)McGaugh, S. E. (2015)Dufton, Megan and Franz-Odendaal, Tamara A. (2015)Stahl, Bethany A. and Gross, Joshua B. (2015)Stahl, B. A., Ma, L and Gross, J. B. (2015)Pennisi, E. (2016)Pennisi, E (2016)Retaux, S., Alie, A., Blin, M., Devos, L., Elipot, Y. and Hinaux, H. (2016)Rohner, Nicolas (2016)Yoshizawa, M., Settle, A., Macaspac, C., Fernandes, V. Yoshida, M. and Keene, A. (2016)Aspiras, A., Tabin, C. and Rohner, N. (2016)Foulkes, N. S., Whitmore, D., Vallone, D and Bertolucci, C. (2016)Casane, D. and Retaux, S. (2016)Lyon, A., Krutzler, A.J., Gross, J.B. and O'Quin, K.E. (2016)Keene, A.C., Yoshizawa, M. and McGaugh, S.E. (2016)O'Quin, K.E., Doshi, P., Lyon, A., Hoenemeyer, E., Yoshizawa, M. and Jeffery, W.R. (2016)Schmitter-Soto, JJ (2016)Beale, A., Whitmore, D. and Moran, D. (2016)Carlson, B.M. and Gross, J.B. (2016)O'Quin, Kelly and McGaugh, Suzanne E. (2016)Atukorala, A. D. S. and Franz-Odendaal, Tamara A. (2016)Beale, A. D. and Whitmore, D. (2016)Gross, J.B., Stahl, B.A., Powers, A.K. and Carlson, B.M. (2016)Stahl, B (2017)Stahl, B.A. and Gross, J.B. (2017)Lyon, A., Powers, A. K., Gross, J. B. and O'Quin, K. E. (2017)Gross, J. B. (2017)Riddle, M (2017)Kaplan, S.A., Powers, A.K. and Gross, J.B. (2017)Jaggard, J. B. (2017)Hinaux, H, Recher, G, Alie, A., Legendre, L, Blin, M. and Retaux, S (2017)Riddle, M. R.; Tabin, C. J (2017)Box, AC (2017)Yoshizawa, M (2017)Krishnan, J and Rohner, N (2017)Alvarado, C.G. (2017)Peña-Herrejón, Guillermo A. Sanchez-Velazquez, Julieta Cruz-Hernández, Andrez Aguirre-Becerra, Humberto García-Trejo, Fernando (2017)Riddle, M (2017)Gore, A.V. (2017)Gore, A.V., Tomins, K.A., Iben, J., Ma, L., Castranova, D., Davis, A.E., Parkhurst, A., Jeffery, W.R. and Weinstein, B.M. (2017)Torres-Paz, J (2017)Wilkens, H. and Strecker, U. (2017)Schmitter-Soto, JJ (2017)Fumey J, Hinaux H, Noirot C, Thermes C, Re´ taux S, Casane D. (2017)Cartwright, R.A., Schwartz, R.C., Merry, A.L. and Howell, M.M. (2017)Fernandes, V (2017)Delić, T., Trontelj, P., Rendoš, M. and Fišer, C. (2017)Pierre, C (2017)Jaggard, J. B., Robinson, B. G., Stahl, B, Oh, I, Masek, P, Yoshizawa, M and Keene, A. (2017)Bussotti, S., Di Franco, Antonio AU - Bianchi, Carlo Nike AU - Chevaldonné, Pierre AU - Egea, Lea AU - Fanelli, Emanuela AU - Lejeusne, Christophe AU - Musco, Luigi AU - Navarro-Barranco, Carlos AU - Pey, Alexis AU - Planes, Serge AU - (2018)Blin, M., Tine, E., Meister, L., Elipot, Y., Bibliowicz, J., Espinasa, L. and Rétaux, S. (2018)Tang, J.L.Y., Guo, Y., Stockdale, W.T., Rana, K., Killen, A.C., Mommersteeg, M.T.M. and Yamamoto, Y. (2018)Stockdale, W.T., Lemieux, M.E., Killen, A.C., Zhao, J., Hu, J., Riepsaame, J. Hamilton, N., Kudoh, T., Riley, P.R., van Aerle, R., Yamamoto, Y. and Mommersteeg, M.T.M. (2018)Ornelas-García, P,. Pajares, S., Sosa-Jiménez, V.M., Rétaux, S. and Miranda-Gamboa, R.A. (2018)Powers, A.K., Kaplan, S.A., Boggs, T.E. and Gross, J. (2018)Sovrano, V.A., Potrich, D., Foà, A. and Bertolucci, C. (2018)Jaggard, J.B., Stahl, B.A., Lloyd, E., Prober, D.A., Duboue, E.R. and Keene, A.C. (2018)Carlson, B.M. and Gross, J.B. (2018)Espinasa, L. (2018)Sears, C.R. and Gross, J.B. (2018)Espinasa, L., Legendre, L., Fumey, J., Blin, M., Rétaux, S. and Espinasa, M. (2018)Stah, B.A., Sears, C.R., Ma, L., Perkins, M. and Gross, J.B. (2018)Mirande, J.M. (2018)Powers, A.K., Boggs, T.E. and Gross, J.B. (2018)Borowsky, R. (2018)Alie, A., Devos, L., Torres-Paz, J., Prunier, L., Boulet, F., Blin, M., Elipot, Y. and Retaux, S. (2018)Tabin, J.A., Aspiras, A., Martineau, B., Riddle, M., Kowalko, J. Borowsky, R. Rohner, N. and Tabin, C.J. (2018)Riddle, M.R., Boesmans, W., Caballero, O, Kazwiny, Y. and Tabin,C.J. (2018)Borowsky, R., Luk, A., He, X.J. and Kim, R.S. (2018)Yoshizawa, M., Settle, A., Hermosura, M.C., Tuttle, L.J., Cetraro, N., Passow, C.N. and McGaugh, S.E. (2018)Fernandes, V.F.L., Macaspac, C., Lu, L. and Yoshizawa, M. (2018)Riddle, M., Martineau, B., Peavey, M. and Tabin, C. (2018)Elliott, W.R. (2018)Riddle, M.R., Aspiras, A.C., Gaudenz, K., Peuß, R., Sung, J.Y., Martineau, B., Peavey, M., Box, A.C., Tabin, J.A., McGaugh, S., Borowsky, R., Tabin, C.J. and Rohner, N. (2018)Lloyd, E., Olive, C., Stahl, B.A., Jaggarda, J.B., Amaral, P., Dubouéa, E.R and Keene, A.C. (2018)Devitsina, G.V. and Golovkina, T.V. (2018)Rohner, N. (2018)Garita-Alvarado, C.A., Barluenga, M. and Ornelas-García, C.P. (2018)Pazza, R., Dergam, J.A. and Kavalco, K.F. (2018)Fumey, J., Hinaux, H., Noirot, C., Thermes, C., Rétaux, S. and Casane, D. (2018)Kopp, J., Avasthi, S. and Espinasa, L. (2018)Gore, A.V., Tomins K.A., Iben, J., Ma, L., Castranova, D., Davis, A.E., Parkhurst, A., Jeffery, W.R. and Weinstein, B.M. (2018)Kling, J. (2018)Ojha, A. and Watve, M. (2018)Torres-Paz,J., Hyacinthe, C., Pierre, C., Retaux, S. (2018)Chin, J.S.R., Gassant, C.E., Amaral, P.M., Lloyd, E., Stahl, B.A., Jaggard, J.B., Keene, A.C. and Duboue, E.R. (2018)Gore, A., Jeffery, W., Retaux, S. and Rohner, N. (2018)Gore, A.V., Rohner, N., Rétaux, S. and Jeffery, W.R. (2018)Stern, D.B and Crandall, K.A. (2018)Ma, L., Strickler, A.G., Parkhurst, A., Yoshizawa, M., Shi, J. and Jeffery, W.R. (2018)Torres-Dowdall, J., Karagic, N., Plath, M. and Riesch, R. (2018)Xiong, S., Krishnan, J., Peuß, F. and Rohner, N. (2018)Ren, X.Y., Hamilton, N., Müller, F. and Yamamoto, Y. (2018)Carlson, B.M., Klingler, I.B., Meyer, B.J. and Gross, J.B. (2018)Klaassen, H., Wang, Y., Adamski, K., Rohner, N. and Kowalko, J.E. (2018)Rohner, N. (2018)Shiriagin, V. and Korsching, S.I. (2018)Gross, J.B., Weagley, J., Stahl, B.A., Ma, L., Espinasa, L. and McGaugh, S.E. (2018)Frøland Steindal, I.V., Beale, A.D., Yamamoto, Y. and Whitmore, D. (2018)Devi, A., Atukorala, S. and Franz-Odendaal, T.A. (2018)Retaux, S. (2018)Powers, A.K., Garita-Alvarado, C., Rodiles, R., Berning, D.J., Gross, J.B. and Ornelas-García, C.P. (2019)Worsham M1, Fernandes, V.F.L., Settle, A., Balaan, C., Lactaoen, K., Tuttle, L.J., Iwashita, M. and Yoshizawa, M.. (2019)Pierre, C., Torres-Paz, J., Froc, C., Callebert, J. and Rétaux, S. (2019)Xiong, S., Krishnan, J., Peuss, R. and Rohner, N. (2019)Peuß, R., Zakibe, Z., Krishnan, J., Merryman, M.S., Baumann, D.P. and Rohner, N. (2019)Potts, H., Stockdale, W.T., Choudhury, R.P. and Mommersteeg, M.T.M. (2019)Gil-Galvez, A., de la Calle Mustienes, E., Neto, A.., Bilandžija, H., Jeffery, W.R., Gómez-Skarmeta, J.L. (2019)Stockdale, W.T., Tang, J.L.Y., Hu, Z., Potts, H., Lemieux, M.E., Yamamoto, Y. and Mommersteeg, M.T.M. (2019)Powers, A.K., Boggs, T.E., Kaplan, S.A., Davis, E.M. and Gross, J.B. (2019)Policarpo, M., Fumey, J., Lafargeas, P., Legendre, L., Naquin, D., Thermes, C., Møller, P.R., Bernatchez, L., García-Machado, E., Rétaux, S. and Casane, D. (2019)Hyacinthe, C., Attia, J. and Retaux, S. (2019)Agnès, F., Devos, L. and Rétaux, S. (2019)Rétaux, S., Bibliowicz, Y., Blin, M., Elipot, Y., Espinasa, L., Hinaux, H. and Tine, E. (2019)Fernández, A.A., Evans, E.I. and Baumann, D.P. (2019)Worsham, M., Fang, J. and Yoshizawa, M. (2019)Blin, M., Fumey, J., Père, S., Pierre, C., Torres-Paz, J., Simon, V., Espinasa, L. Legendre, L., Casane, D. and Rétaux, S. (2019)Ma, L. and Jeffery, W.R. (2019)Pennisi, E. (2019)Boggs, T.E. and Gross, J.B. (2019)Duboue, E. (2019)Garduño-Sánchez, M.A.A. and Ornelas-García, C.P. (2019)Peuß, R., Box, A.C., Wang, Y., Chen, S., Krishnan, J., Tsuchiya, D., Peak, A., Perera, A., Slaughter, B. and Rohner, N. (2019)Yoshizawa, M., Valdez, C., Balaan, C., Lactaoen, K., Kato, J., Ito, M., Yew, J. and Iwashita, M. (2019)Stahl, B.A., Peuß, R., McDole, B., Kenzior, A., Jaggard, J.B., Gaudenz, K., Krishnan, J., McGaugh, S.E., Duboue, E.R., Keene, A.C and Rohner, N. (2019)Hernández, J., Garita-Alvarado, C.A. and Ornelas-García, C.P. (2019)Espinasa, L., Retaux, S., Yoshisawa, M., Heintz, C. and Balogh- Robinson, R. (2019)Stahl, B.A., Peuß, R., McDole, B., Kenzior, A., Jaggard, J.B., Gaudenz, K., Krishnan, J., McGaugh, S.E., Duboue, E.R., Keene, A.C. and Rohner, N. (2019)Gluesenkamp, A. and McGaugh, S. (2019)Stockdale, W.T., Deal, O., Heintz, C., Rohner, N., and Mommersteeg, M.T.M. (2019)Kindl, G.H. and O’Quin, K.E. (2019)Gore, A., Swearer, A., Iben, J. and Weinstein, B. (2019)Chin, J.S.R., Loomis, C.L., Phan, T.A.N., Albert, L.T., Chang, L.P., Keene, A.C. and Duboué, E.R. (2019)Blin, M. and Retaux, S. (2019)Keene, A.C. (2019)Hu, Z., Lemieux, M. and Mommersteeg, M. (2019)Borowsky, R. (2019)Warren, W.C., Koren, S., Meyer, A. and Rohner, N. (2019)Luc, H., Sears, C., Raczka, A. and Gross, J.B. (2019)Leclercq, J., Torres-Paz, J. and Rétaux, S. (2019)McGaugh, S.E., Passow, C., Jaggard, J.B., Stahl, B. and Keene, A. (2019)Wilkens, H (2019)Legendre, L., Pere, S. and Rétaux, S. (2019)Fernandes, V.F.L., Hernandez, H., Doeden, N. and Yoshizawa, M. (2019)Devos, L., Edouard, J., Simon, V., Agnès, F., Sohm, F. and Rétaux, S. (2019)Legendre, L., Guillet, B., Leguay, E., Meunier, E., Keck, N. and Sohm, F. (2019)Atukorallaya, D., Bhatia, V. and Ratnayake, R. (2019)Jaggard, J., Lloyd, E., Loomis, C., Cook, C., Vega, P., McGaugh, S., Rohner, N., Bohrner, J., Duboue, E. and Keene, A.C. (2019)O’Gorman, M., Lewis, P., Keene, A., Kowalko, J. and Duboué, E. (2019)Loomis, C., Peuss, R., Green, M., McGaugh, S.E., Rohner, N., Keene, A.C. and Duboue, E.R. (2019)Riddle, M., Damen, F., Aspiras, A., Tabin, J., McGaugh, S. and Tabin, C. (2019)Lloyd, E., Olive, C., Stahl, B.A., Jaggard, J.B., Amaral, P., Duboué, E.R. and Keene, A.C. (2019)McDole, B., Jaggard, J., Duboue, E. and Keene, A.C. (2019)Torres-Paz, J., Leclercq. J. and Rétaux, S. (2019)Kowalko, J.E. (2019)Paz, A., McDole, B., Duboue, E. and Keene, A.C. (2019)Krishnan, J. and Rohner, N. (2019)Bilandžija, H., Hollifield, B., Steck, M., Meng, G., Ng, M., Bedek, J., Ćetković, H., Porter, M., Renner, K.J. ands Jeffery, W.R. (2019)Imarazene, B., Herpin, A., Feron, R., Postlethwait, J.H., Schartl, M., Retaux, S. and Guiguen, Y. (2019)van der Weele, C.M. and Jeffery, W.R. (2019)Phelps, A. and Gross, J. (2019)Ornelas-García, C.P., Pajares, S., Sosa-Jiménez, V.M., Rétaux, S. and Gamboa-Miranda, R. (2019)Sifuentes-Romero I. and Kowalko, J.E. (2019)Palluzzi, T., Rowland, R. and Gross, J. (2019)Jeffery, W.R., Ma, L., Shi, J., Ng, M. and Gore,A. (2019)Stahl, B.A., Jaggard, J.B., Chin, J.S., Kowalko, J.E., Keene, A.C. and Duboué, E.R. (2019)Mogdans, J. (2019)